Bruno graduated at the University Gent, Belgium. In subsequent postdocs he performed research on lactic acid bacteria. In 1997 he joined the company Yakult as science manager Benelux. Between 2001–2016 he worked as Research Director at the Institut Pasteur in Lille and as Director Business Development at the bioinformatics company Applied Maths. Since 2016 Bruno is back with Yakult as Science Director Europe. He is member of the Taxonomic Subcommittee for Lactobacillus and Bifidobacterium, Vice-President of the Pharmabiotic Research Institute, Board Chair of ILSI-Europe, and Professor at the Vrije Universiteit Brussel since 2001 for courses in food microbiology.